Do non-opioid drugs with alternative pain management therapies provide better pain management than opioid therapy over six months?

By the due date assigned write a 2-3-page paper addressing the sections below of the research proposal.
Introduction

Background and Significance of the Problem
Statement of the Problem and Purpose of the Study

Research Questions, Hypothesis, and Variables with Operational Definitions

Research Question
Hypothesis: Research and Null
Identifying and Defining Study Variables
Operationalize Variables

My research questions is “ Do non-opioid drugs with alternative pain management therapies provide better pain management than opioid therapy over six months?”

Please do not forget to include alternative therapies and to develop the research question. 
Thank you and let me know if you have any questions.